Radical Hysterectomy in Cervical Neuroendocrine Carcinoma with Michael Frumovitz

In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Michael Frumovitz to discuss radical hysterectomy in cervical neuroendocrine carcinoma. Dr. Frumovitz is an Associate Editor for IJGC and the author of the Lead Article of the April 2021 issue of IJGC, “Role of radical hysterectomy in patients with early-stage high-grade neuroendocrine cervical carcinoma: a NeCTuR study" (https://ijgc.bmj.com/content/early/2021/03/09/ijgc-2020-002213). Highlights: 1. Patients with clinical and radiologic stage I high grade neuroendocrine carcinoma of the cervix will have microscopic parametrial involvement 10% of the time 2. All patients with parametrial involvement will have other risk factors requiring postoperative radiation (positive nodes or Sedlis) 3. If a patient has negative nodes, the risk of parametrial involvement is only 3% 4. Eighty percent of recurrences will happen within first two years and 86% destined to recur will recur within 3 years