Obesity , Leptin & Risk of Autoimmunity: a Problem in Achieving Herd Immunity
High Intensity Health with Mike Mutzel, MS - Ein Podcast von Author Mike Mutzel interviews Jeff Bland, Datis Kharrazian, Ben Greenfield, Abel James, Dave Asprey, Ben Lynch, Jade Teta and Corey chuler
Scientists find lean subjects made protective antibodies after infection while obese subjects did not make protective antibodies—they made maladaptive autoantibodies instead. Researchers speculate that leptin plays a role in skewing the immune response toward autoimmunity after infection. Here's the details! Related: Save your seat in the upcoming Blood Work MasterClass Live Training RSVP Here: https://courses.highintensityhealth.com/store/hgwDdo2p Research, Images and Articles: https://bit.ly/3qsGYX6 Time Stamps: 0:00 Intro 0:09 Endemic Virus 0:59 Obese Don't Make Protective Antibodies 1:15 Obese people make autoantibodies 1:40 Leptin and Fat on Fire 2:40 Leptin exacerbates inflammation, autoimmunity 3:13 Study we're discussing 3:49 Make Americans Healthy Again 4:35 Blood Work MasterClass 5:30 Daniela Frasca, PhD: Obesity Hinders Immune System Response 6:10 Antibodies and BMI, C-Reactive Protein 6:43 Metainflammation and Inflammaging 7:15 Blood sugar and inflammation 8:13 Leptin and immunity 9:29 Summary of Study: immune tolerance breakdown 11:30 Lifestyle matters 12:30 Antibodies directed at fat tissue 12:52 Omega-6 Oils, Seed Oils & autoimmunity 13:50 Excess deaths related to heart disease on the rise 14:42 Image: CRP and autoantibodies 15:39 New study summary 16:21 Italy Research from fat cell spill over 16:58 Obesity is an autoimmune disease 17:05 Change your habits 17:47 Image: Behavior model Books and References: Tiny Habits: The Small Changes That Change Everything: https://amzn.to/3CbpvEQ Frasca, D., Reidy, L., Cray, C., Diaz, A., Romero, M., Kahl, K., & Blomberg, B. B. (2021). Influence of obesity on serum levels of SARS-CoV-2-specific antibodies in COVID-19 patients. Plos One, 16(3), e0245424–16. Frasca, D., Reidy, L., Romero, M., Diaz, A., Cray, C., Kahl, K., & Blomberg, B. B. (2021). The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing. International Journal of Obesity, 1–6.
